Vertex Pharmaceuticals VRTX

Vertex Pharmaceuticals is the 90th largest S&P 500 company by market cap, worth $133 billion. 11 directors have filed with the SEC in the last 12 months (who counts), 2 of them executives. 11 other officers are on file. At 30 Jun 2026, Capital Group was its largest institutional holder, with 20.0% of the company.

CEO
Reshma Kewalramani
Chair
Jeffrey M. Leiden
Sector
Health Care
Sub-industry
Biotechnology
Headquarters
Boston, Massachusetts
Founded
1989
Market cap
$133B
90th largest, 23 Oct 2026 close
Revenue
$12.0B
Fiscal year 2025
Price to sales
11.1
Market cap over revenue
Employees
6,400
10-K, 31 Dec 2025
Market cap per employee
$21M
Market cap over employees
Connections
5
S&P 500 companies sharing a director or officer

Largest institutional holders

Each fund group's share of Vertex Pharmaceuticals. Where a company has several share classes, the share is of its total value.

13F filings for the quarter to 30 Jun 2026

These five hold 46.9% of Vertex Pharmaceuticals.

Board and officers

5 people here also hold roles at other S&P 500 companies.

Roles filed up to 30 Sep 2026

NameTitle
Directors (11)
Jeffrey M. LeidenExecutive ChairmanLast filed 26 Feb 2026Executive Chairman
Reshma KewalramaniCEO & PresidentLast filed 3 Mar 2026CEO & President
Sangeeta N. BhatiaDirectorDirector
Lloyd CarneyDirectorAlso at VisaDirector
Alan M. GarberDirectorDirector
Michel LagardeDirectorAlso at West Pharmaceutical ServicesDirector
Diana McKenzieDirectorAlso at MetLifeDirector
Bruce I. SachsDirectorDirector
Jennifer SchneiderDirectorDirector
Nancy ThornberryDirectorDirector
Suketu UpadhyayDirectorAlso at IncyteDirector
Officers (11)
David AltshulerEVP, Chief Scientific OfficerLast filed 26 Jan 2026EVP, Chief Scientific Officer
Kristen AmbroseSVP & Chief Accounting OfficerLast filed 1 Sep 2026SVP & Chief Accounting Officer
Edward Morrow Atkinson IIIEVP, Chief Technical Ops. OffLast filed 26 Feb 2026EVP, Chief Technical Ops. Off
Carmen BozicEVP and CMOLast filed 30 Jun 2026EVP and CMO
Mark E. BunnageEVP, Chief Scientific OfficerLast filed 19 May 2026EVP, Chief Scientific Officer
Jasper van GrunsvenEVP, CP and NPPOLast filed 10 Sep 2026EVP, CP and NPPO
Joy LiuEVP and Chief Legal OfficerLast filed 6 Jul 2026EVP and Chief Legal Officer
Duncan McKechnieEVP, Chief Commercial OfficerLast filed 7 Jul 2026EVP, Chief Commercial Officer
Amit SachdevEVP Chief Patient & Ext Af OffLast filed 23 Jul 2026EVP Chief Patient & Ext Af Off
Ourania TatsisEVP, Chief Reg. & Quality OffLast filed 23 Jul 2026EVP, Chief Reg. & Quality Off
Charles F. Wagner Jr.EVP, Co & FoAlso at TJX CompaniesLast filed 26 Feb 2026EVP, Co & Fo

Companies that share people with Vertex Pharmaceuticals

Each person's title here, then at the other company.

  • Incyte INCY
    • Suketu Upadhyay: Director here, EVP & Chief Financial Officer there
  • MetLife MET
    • Diana McKenzie: Director here, Director there
  • TJX Companies TJX
    • Charles F. Wagner Jr.: EVP, Co & Fo here, Director there
  • Visa V
    • Lloyd Carney: Director here, Director there
  • West Pharmaceutical Services WST
    • Michel Lagarde: Director here, President and CEO there

Vertex Pharmaceuticals' market cap since December 2008

Marked weeks are changes in the share count, such as a merger, not market moves.

Weekly, up to 23 Oct 2026

Show equal percentage changes as equal steps.
201020122014201620182020202220242026$133B

Workforce

Headcount at 31 Dec 2025

Employees
6,400
As of December 31, 2025 , we had approximately 6,400 employees.
Vertex Pharmaceuticals Form 10-K

Insider trades

Open-market buys and sales by directors and officers. Grants, option exercises and shares withheld for tax are left out.

Trades from 30 Sep 2025 to 30 Sep 2026

Directors and officers sold $158 million of stock in 59 sales and made no open-market purchases in the 12 months to 30 Sep 2026.

DatePersonTitleTypeSharesValue
2 Jul 2026SaleDuncan McKechnieEVP, Chief Commercial OfficerEVP, Chief Commercial OfficerSale1,541$800K
2 Jul 2026SaleOurania TatsisEVP, Chief Reg. & Quality OffEVP, Chief Reg. & Quality OffSale1,500$787K
1 Jul 2026SaleJoy LiuEVP and Chief Legal OfficerEVP and Chief Legal OfficerSale828$416K
26 Jun 2026SaleCarmen BozicEVP and CMOEVP and CMOSale596$288K
18 Jun 2026SaleCarmen BozicEVP and CMOEVP and CMOSale1,020$471K
15 Jun 2026SaleCarmen BozicEVP and CMOEVP and CMOSale4,062$1.8M
5 Jun 2026SaleCarmen BozicEVP and CMOEVP and CMOSale1,745$785K
1 Jun 2026SaleJoy LiuEVP and Chief Legal OfficerEVP and Chief Legal OfficerSale828$364K
29 May 2026SaleCarmen BozicEVP and CMOEVP and CMOSale1,974$888K
15 May 2026SaleCarmen BozicEVP and CMOEVP and CMOSale1,354$614K

Showing 10 of 59 trades

Trades by members of Congress and officials

Trades members of Congress and senior executive branch officials disclosed, including their families'. Amounts are filed as ranges.

Trades from 20 Oct 2023 to 20 Oct 2026

11 people disclosed 17 purchases and 17 sales of Vertex Pharmaceuticals stock since October 2023.

DateMember or officialTypeAmount
4 Sep 2026Rohit Khanna (House, D-CA)House, D-CA 路 BoughtPurchase$1,001 to $15,000$1K to $15K
26 Aug 2026David J. Taylor (House, R-OH)House, R-OH 路 SoldSale$1,001 to $15,000$1K to $15K
13 Apr 2026Rohit Khanna (House, D-CA)House, D-CA 路 BoughtPurchase$1,001 to $15,000$1K to $15K
27 Mar 2026Alan Armstrong (Senate, R-OK)Senate, R-OK 路 BoughtPurchase$1,001 to $15,000$1K to $15K
30 Jan 2026Arjun Mody (Deputy Commissioner)Deputy Commissioner 路 SoldSale$1,001 to $15,000$1K to $15K
29 Jan 2026David J. Taylor (House, R-OH)House, R-OH 路 SoldSale$1,001 to $15,000$1K to $15K
23 Jan 2026Rohit Khanna (House, D-CA)House, D-CA 路 BoughtPurchase$1,001 to $15,000$1K to $15K
7 Oct 2025Rohit Khanna (House, D-CA)House, D-CA 路 BoughtPurchase$1,001 to $15,000$1K to $15K
29 Sep 2025Rohit Khanna (House, D-CA)House, D-CA 路 BoughtPurchase$1,001 to $15,000$1K to $15K
5 Sep 2025Rohit Khanna (House, D-CA)House, D-CA 路 SoldSale$1,001 to $15,000$1K to $15K

Showing 10 of 34 trades

WARN layoff notices

Notices filed under Vertex Pharmaceuticals' own name. Subsidiaries that file under their own names are not included.

Notices from 26 Oct 2023 to 26 Oct 2026

Vertex Pharmaceuticals filed 1 notice covering 125 workers since October 2023.

NoticePlaceWorkersEffective
8 Jun 2025Providence, RI1255 Aug 2025